Yield Optimization Based on DoE

Design processes that optimize product yields and meet regulatory requirement.

TFF Development

Monitor and adjust transmembrane pressure (TMP) cutoff ,membrane area,shear force  and cross flow rate to optimize  phage product yield.

Optimize buffer system to maximize phage recovery yield and stability.

Chromatography Development

Enhance purity and recovery

In-house column packing and qualification

Resin screening and selection

Column cycling and aging studies

Reduction of process residuals

Formulation Development

Cryoprotectant and excipient screening to enhance the stability of phage product.

Stability studies and testing.

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